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(a) Free state of ABCE1 (PDB 3BK7; ref. 10); intermediate, semi-closed pre-splitting state bound to 80S ribosomes (PDB 4CRM; ref.

Extended Data Figure 5: Additional details on Pol I EC.

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Yellow, cPml1p; blue, cBud13p; red, C-terminal α-helix of cSnu17p; pink, connecting loop; black, body of the RRM ...

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a,b, Two-dimensional views of 42,411 T = 4 particles were calculated by maximum-likelihood-based classification in RELION. An asymmetric RNA feature is ...

a, Two perpendicular views of the crystal structure of SRA are shown, together with a schematic model in which the helices are represented as rectangles.

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action | Nature

Fig. 5

The N-lobe and C-lobe of CDK2 are coloured in grey and pink, respectively, and KAP is coloured in green.

a, The particle was pinned at a single point of the top glass surface and exhibited rotational Brownian motion. To impose a tilted periodic potential on the ...

a, Diagram of the structural elements of LCM. b, Half core structure, including LCM, LC, and the core layers A1, A2, A3 and B1. The PB loop in the ...

Structure and mutagenesis reveal essential capsid protein interactions for KSHV replication | Nature

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The structures of wild-type proteasome in its substrate-free (left) and substrate-engaged state (right) identically oriented on the basis of their 20S ...

Cryo-EM shows how dynactin recruits two dyneins for faster movement | Nature

Graphical abstract

a, Interface between TMD of G5 and inactive NBS1: connecting (CnH) and coupling (CpH) helices (blue), ABC Signature motifs (orange), Q-loops (purple) and ...

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Panels are arrestin finger loop with rhodopsin TM7 and helix 8 (a); arrestin middle loop with rhodopsin ICL2 (b); arrestin C-loop residue Y251 ...

(a) Mat2A regions exhibiting changes in HDX are shown as colored regions on one monomer of the Mat2A dimer in complex with Mat2B (PDB ID: 4NDN) with ...

EPR spectra of 32-TOAC-Noxa free in solution (black) and in the presence of excess Mcl-1 (red), in the absence (a) and presence (b) of phosphorylation at ...

The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells | Nature Immunology

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10 ways to make physical science FUN!

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... the radioiodinated antagonist cyanopindolol ([125I]CYP) binding with isoproterenol in β2AR reconstituted within HDL particles in the presence or absence ...

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Figure 6

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a, Production of clinical lots by using adherent MSCs in 2D cell-culture plates. Issues with the scaling of costs and labour efficiency make 2D culture ...

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Single-peptide DNA-dependent RNA polymerase homologous to multi-subunit RNA polymerase | Nature Communications

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Architecture and conformational switch mechanism of the ryanodine receptor | Nature

MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping | Nature Immunology

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... dimer with KPT-9274. a The crystal structure of NAMPT dimer with KPT-9274 is depicted as a cartoon with the NAMPT monomers shown in light blue and pink ...

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New York State Attorney General Eric T. Schneiderman and state Assemblyman Robert K. Sweeney have unveiled a proposed law to prohibit the sale in the state ...

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Z-Averages of the particles are plotted against the measured temperature (25–90 °C). The Z-averages of AaLS-neg ...

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